The establishment and operation of a pediatric intravenous medication administration program is described. A program was developed in which a team of pharmacists rotate between assignments in a pharmacy satellite providing unit dose distribution for 87 pediatric beds and an intravenous medication administration program serving a 15-bed pediatric isolation unit. Staffing patterns, pharmacy responsibilities, and a six-week training program for pharmacists are described. The i.v. medication administration program has been well received by nurses and physicians, and pediatric pharmacy personnel view themselves as functioning, productive members of the health care team. Audits indicate the pharmacy-controlled i.v. medication administration program has favorably affected patient care.